Interleukin-6: a potential mediator of the massive osteolysis in patients with Gorham-Stout disease.

Massive osteolysis ( Gorham,s disease) and report a case

Gotham's disease or vanishing bone is a rare disease with unknown etiology. Frequently, children and young adults are affected. It is characterized by proliferation of vascular or lymphatic tissue which results in destruction and resorption of bone. In this disease, the destructed bone is replaced either by hemangiomatous or lymphangiomatous tissue ( s) and in a later stage, fibrosis occurs. It...

The Gorham-Stout syndrome (Gorham's massive osteolysis). A report of six cases with histopathological findings.

The Gorham-Stout Syndrome (Gorham's massive osteolysis) is a rare condition in which spontaneous, progressive resorption of bone occurs. The aetiology is poorly understood. We report six cases of the condition and present evidence that osteolysis is due to an increased number of stimulated osteoclasts. This suggests that early potent antiresorptive therapy such as with calcitonin or bisphosphon...

Mandibular Gorham–Stout disease

RATIONALE Gorham-Stout disease (GSD) is characterized by aggressive bone resorption, proliferation of vascular or lymphatic vessels, and soft-tissue swelling. Bones that initially appear normal start to resorb, partially or completely. However, the etiology of GSD is unknown. PATIENT CONCERNS A 29-year-old man with a chief complaint of toothache and mobility in the lower right mandible for th...

[The malignant degeneration of Gorham-Stout disease?].

Increased Intracranial Pressure in a Boy with Gorham-Stout Disease

Gorham-Stout disease (GSD), also known as vanishing bone disease, is a rare disorder, which most commonly presents in children and young adults and is characterized by an excessive proliferation of lymphangiomatous tissue within the bones. This lymphangiomatous proliferation often affects the cranium and, due to the proximate location to the dura surrounding cerebrospinal fluid (CSF) spaces, ca...